Katalin Karikó and Drew Weissman are the 2023 Nobel Prize winners in Medicine for their discoveries

His Discoveries is nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19

Their research has had a profound impact on the world, helping to end the COVID-19 pandemic and paving the way for new mRNA vaccines against other diseases.

Karikó and Weissman's journey to the Nobel Prize began in the 1980s.

Karikó was a biochemist working at the University of Pennsylvania, and Weissman was an immunologist

At the time, mRNA vaccines were still in their early stages of development. mRNA vaccines work by delivering a strand of messenger RNA (mRNA) into the body. 

The COVID-19 mRNA vaccines have been incredibly successful. They have saved millions of lives and helped to end the pandemic.

Katalin Karikó and Drew Weissman are two of the most important scientists of our time. They are truly deserving of the 2023 Nobel Prize in Medicine.